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Fig. 3 | Cancer Cell International

Fig. 3

From: Exosome-transferred hsa_circ_0014235 promotes DDP chemoresistance and deteriorates the development of non-small cell lung cancer by mediating the miR-520a-5p/CDK4 pathway

Fig. 3

NSCLC serum-derived exosomes strengthened DDP chemoresistance in vivo. A549 cells were injected into the nude mice, and the mice were treated with PBS or Exo and administered with or without DDP. a Tumor volume in each group was measured once a week. b Tumor weight in each mouse was measured after 5 weeks. c The expression of hsa_circ_0014235 in removed tumor tissues was detected by qPCR. d The expression of MMP9, Bax, E-cadherin, Vimentin and MRP-1 in removed tumor tissues was measured by western blot. *P < 0.05, **P < 0.01, ***P < 0.001

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