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Table 1 Patient information

From: Extracellular vesicle-associated miR-135b and -135a regulate stemness in Group 4 medulloblastoma cells by targeting angiomotin-like 2

Patient no Gender Age Genetic profile Histology M stagea Location EOR Follow-up
1 F 15 y Medulloblastoma, WNT-activated Classic M0 Rt. Cbll GTR NED, alive (26 m)
2 M 8  y Medulloblastoma, SHH-activated Large cell/anaplastic M0 Rt. Cbll GTR Recurred at 12 m, PD, expired (17 m)
3 F 5 y Medulloblastoma, SHH-activated Large cell/anaplastic M0 Lt. Cbll GTR Recurred at 9 m, PD, expired (15 m)
4 M 5 y Medulloblastoma, group 3 With extensive nodularity M0 4 V STR NED, alive (48 m)
5 M 3 y Medulloblastoma, group 3 Classic M3 4 V GTR Recurred at 9 m, PD, expired (12 m)
6 M 10 y Medulloblastoma, group 3 Large cell/anaplastic M3 4 V NTR Recurred at 1 m, PD, alive (42 m)
7 F 12 y Medulloblastoma, group 4 Large cell/anaplastic M0 4 V NTR NED, alive (23 m)
8 F 7 y Medulloblastoma, group 4 Classic M0 4 V NTR NED, alive (26 m)
9 M 7 y Medulloblastoma, group 4 With extensive nodularity M1 4 V NTR Recurred at 22 m, PD, expired (37 m)
10 F 6 y Medulloblastoma, group 4 Classic M0 4 V GTR NED, alive (15 m)
  1. F female, M male, y years, MBEN medulloblastoma with extensive nodularity, Cbll cerebellum, 4V fourth ventricle, EOR extent of resection, GTR gross total resection, STR subtotal resection, NTR near total resection, m months, NED no evidence of disease, PD progressive disease
  2. a M stage (Chang’s classification) [47]. M0: no metastasis; M1: presence of tumor cells in the CSF; M2: nodular seeding in the cerebellar or cerebral subarachnoid space or in the third or lateral ventricle; M3: metastasis in spinal subarachnoid space; M4: metastases outside the cerebrospinal axis