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Table 5 The association between SNPs of NINJ2 and clinical index of endometrial cancer

From: Ninjurin 2 rs118050317 gene polymorphism and endometrial cancer risk

SNP

Clinical Index

Genotype

Number in cases

Quantity in blood (mean ± SD)

p

rs7307242

CEA (ng/ml)

AA

7

14.94 ± 3.97

0.021*

  

AT

69

11.56 ± 3.55

 
  

TT

229

12.78 ± 4.01

 
 

AFP (ng/ml)

AA

7

19.55 ± 21.16

< 0.001*

  

AT

69

9.23 ± 3.82

 
  

TT

227

9.61 ± 4.23

 

rs75750647

CA125 (U/ml)

AA

35

46.51 ± 131.23

0.032*

  

AG

129

24.09 ± 44.88

 
  

GG

135

18.6 ± 24.39

 
 

CA199 (U/ml)

AA

31

46.19 ± 163.92

0.033*

  

AG

124

15.9 ± 14.45

 
  

GG

130

20.32 ± 28.95

 

rs11610368

HE4 (pg/ml)

AA

3

295.38 ± 390.97

0.010*

  

AG

65

90.37 ± 99.74

 
  

GG

233

91.49 ± 113.83

 
  1. CEA carcinoembryonic antigen, CA carbohydrate antigen, HE4 human epididymis protein 4, AFP alpha fetoprotein, SF serum ferritin, TNF tumor necrosis factor
  2. *p < 0.05 indicates statistical significance