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Table 5 The association between SNPs of NINJ2 and clinical index of endometrial cancer

From: Ninjurin 2 rs118050317 gene polymorphism and endometrial cancer risk

SNP Clinical Index Genotype Number in cases Quantity in blood (mean ± SD) p
rs7307242 CEA (ng/ml) AA 7 14.94 ± 3.97 0.021*
   AT 69 11.56 ± 3.55  
   TT 229 12.78 ± 4.01  
  AFP (ng/ml) AA 7 19.55 ± 21.16 < 0.001*
   AT 69 9.23 ± 3.82  
   TT 227 9.61 ± 4.23  
rs75750647 CA125 (U/ml) AA 35 46.51 ± 131.23 0.032*
   AG 129 24.09 ± 44.88  
   GG 135 18.6 ± 24.39  
  CA199 (U/ml) AA 31 46.19 ± 163.92 0.033*
   AG 124 15.9 ± 14.45  
   GG 130 20.32 ± 28.95  
rs11610368 HE4 (pg/ml) AA 3 295.38 ± 390.97 0.010*
   AG 65 90.37 ± 99.74  
   GG 233 91.49 ± 113.83  
  1. CEA carcinoembryonic antigen, CA carbohydrate antigen, HE4 human epididymis protein 4, AFP alpha fetoprotein, SF serum ferritin, TNF tumor necrosis factor
  2. *p < 0.05 indicates statistical significance