Hsa_circ_0004831 serves as a blood-based prognostic biomarker for colorectal cancer and its potentially circRNA-miRNA-mRNA regulatory network construction

Table 2 Correlation between hsa_circ_0004831 expression and clinicopathological characteristics

Characteristics	No. of patients	hsa_circ_0004831 (M ± SEM)	t value	p
Age (years)
≥ 50	45	5.59 ± 0.27	0.37	0.715
< 50	36	5.73 ± 0.25	0.37	0.715
Gender
Male	47	5.50 ± 0.23	1.06	0.291
Female	34	5.89 ± 0.29	1.06	0.291
Distant metastasis
M0	36	5.18 ± 0.28	2.43	0.018*
M1	45	6.06 ± 0.23	2.43	0.018*
TNM stage
I + II	33	5.75 ± 0.26	0.36	0.718
III + IV	48	5.61 ± 0.25	0.36	0.718
Differentiation grade
Well/moderate	42	5.28 ± 0.24	2.26	0.027*
Poor	39	6.09 ± 0.26	2.26	0.027*
Lymph node metastasis
Negative	35	5.70 ± 0.27	0.15	0.880
Positive	46	5.64 ± 0.25	0.15	0.880

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