Fig. 5
From: FABP7 is a potential biomarker to predict response to neoadjuvant chemotherapy for breast cancer
FABP7 enhances drug sensitivity by promoting G1/S transition in cell cycle. a The relative protein level of FABP7, ESR1, Cdh1, Skp2, p27 in overexpressed FABP7 MDA-MB-231-ADR and control group cells. b The effect of over expression FABP7 on cell cycle in MDA-MB-231-ADR cells. c The cell viability analysis of pCMV-FABP7 and pCMV in MDA-MB-231-ADR cells after treating with doxorubicin. d The relative protein level of FABP7, ESR1, Cdh1, Skp2, p27 in decreased expressed FABP7 MDA-MB-231 and control group cells. e The effect of silencing FABP7 on cell cycle in MDA-MB-231-ADR cells. f The cell viability analysis of siFABP7 and siNC in MDA-MB-231 cells after treating with doxorubicin. g The schematic representation of how FABP7 promotes proliferation and the relationship FABP7 and chemoresistance