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Fig. 3 | Cancer Cell International

Fig. 3

From: Parthenolide inhibits the growth of non-small cell lung cancer by targeting epidermal growth factor receptor

Fig. 3

Parthenolide inhibits the EGFR signaling pathway in EGFR mutated NSCLC cells. H1975, PC-9 and HCC827 cells were treated by parthenolide at different concentrations (0, 2.5, 5 and 10 µM) for 24 h. Whole cell lysate was probed to EGFR, phospho EGFR, AKT, phospho AKT (T473 and T308), phospho ERK, ERK and with GAPDH as a loading control. The results are respresentative of three independent experiments. *P < 0.05. **P < 0.01. ***P < 0.001 for comparison between control group and parthenolide-treated group

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