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Fig. 2 | Cancer Cell International

Fig. 2

From: Exosomes from tamoxifen-resistant breast cancer cells transmit drug resistance partly by delivering miR-9-5p

Fig. 2

Exosomes from MCF-7/TAM cells confers drug resistance in the parental MCF-7 cells. a The cell viability of MCF-7 cells after TAM treatment determined by CCK-8. b IC50 values of MCF-7 cells treated with TAM. c The cell cycle distribution of MCF-7 in the presence of MCF-7/TAM-exo, analyzed by flow cytometry. d The apoptosis of MCF-7 cells in the presence of MCF-7/TAM-exo, analyzed by flow cytometry. e Western blot analysis of stemness markers KIT, CD44, and CD24 in MCF-7 cells in the presence of MCF-7/TAM-exo. f Sphere-forming abilities of MCF-7 cells in the presence of MCF-7/TAM-exo were examined by 3-D cell culture (scale bar: 50 μm). *p <0.05. All experiments were conducted three times independently

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