Fig. 1From: Resveratrol, curcumin, paclitaxel and miRNAs mediated regulation of PI3K/Akt/mTOR pathway: go four better to treat bladder cancerSchematic representation of mTOR signaling cascade. Classical mTOR signaling cascade is triggered by the binding of ligand to insulin receptor that causes the activation of PI3K and finally initiation of signal transduction from mTORC1 and mTORC2 complexes that allows translation of targeted genes and cytoskeleton rearrangementsBack to article page