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Fig. 4 | Cancer Cell International

Fig. 4

From: Resveratrol, curcumin, paclitaxel and miRNAs mediated regulation of PI3K/Akt/mTOR pathway: go four better to treat bladder cancer

Fig. 4

MiRNAs under the influence of resveratrol, curcumin and paclitaxel efficiently inhibit the downstream signaling cascades that in turn promote the apoptosis and stop cell growth. These compounds mediated signaling up-regulates PTEN expression, inhibits Akt activation and also regulates activation of mTOR signaling-downstream effector molecules. Red up-arrow in diagram presents up-regulation while red down-arrow presents down-regulation

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