Fig. 4From: Resveratrol, curcumin, paclitaxel and miRNAs mediated regulation of PI3K/Akt/mTOR pathway: go four better to treat bladder cancerMiRNAs under the influence of resveratrol, curcumin and paclitaxel efficiently inhibit the downstream signaling cascades that in turn promote the apoptosis and stop cell growth. These compounds mediated signaling up-regulates PTEN expression, inhibits Akt activation and also regulates activation of mTOR signaling-downstream effector molecules. Red up-arrow in diagram presents up-regulation while red down-arrow presents down-regulationBack to article page