Skip to main content
Fig. 3 | Cancer Cell International

Fig. 3

From: Aurora-B knockdown inhibits osteosarcoma metastasis by inducing autophagy via the mTOR/ULK1 pathway

Fig. 3

Silencing Aurora-B induces OS cells autophagy by suppressing the mTOR/ULK1 pathway. Aurora-B silencing and corresponding contrast OS cells were used to measure examine the mTOR/ULK1 pathway signaling and autophagy. The protein levels of AMKP, p-AMPK, mTOR, p-mTOR, ULK1, and p-ULK1 in Aurora-B B-knocked down 143B, and HOS cells were analyzed by western blotting (a). Treated Following treatment of these OS cells with or without MHY-1485 (2 μM, 3 h) in these OS cells, or not, the expression of P62p62, p-mTOR, and mTOR was detected investigated by western blotting (b)

Back to article page
\