Skip to main content
Fig. 6 | Cancer Cell International

Fig. 6

From: Aurora-B knockdown inhibits osteosarcoma metastasis by inducing autophagy via the mTOR/ULK1 pathway

Fig. 6

Aurora-B knockdown inhibits metastasis via mTOR-mediated autophagy in vivo. 143B cells stably expressing firefly luciferase were inoculated into the tibia of female BALB/C nude mice (n = 6) to establish an orthotopic model of spontaneous OS (a). After 6 weeks, mice were dissected and luminescence signals were detected (b). Then, the number of mice with metastases was counted (c). Representative H&E staining sections of the lungs were visualized by microscopy (d). Scale bars: 1000 μm (left images) and 400 μm (right images)

Back to article page