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Table 1 Correlation of Aurora-B protein expression levels in OS tissues with clinical pathologic parameters

From: Aurora-B knockdown inhibits osteosarcoma metastasis by inducing autophagy via the mTOR/ULK1 pathway

Variables

All cases

Aurora-B expression

P value

Low

High

Gender

 Male

40

19 (47.5%)

21 (52.5%)

0.328

 Female

29

18 (62.1%)

11 (37.9%)

 

Age

  ≤ 20

33

19 (57.6%)

14 (42.4%)

0.631

  > 20

36

18 (50%)

18 (50%)

 

Location

 Femur/Tibia

53

27 (50.9%)

26 (49.1%)

0.569

 Elsewhere

16

10 (62.5%)

6 (37.5%)

 

Tumor size (cm)

  ≤ 5

23

16 (69.6%)

7 (30.4%)

0.076

  > 5

46

21 (45.7%)

25 (54.3%)

 

Enneking staging

 I + IIA

40

26 (65%)

14 (35%)

0.031*

 IIB + III

29

11 (37.9%)

18 (62.1%)

 

LC3B expression

 Low

34

13 (38.2%)

21 (61.8%)

0.016*

 High

35

24 (68.6%)

11 (31.4%)

 
  1. P value was calculated by Pearson’s Chi-Square test. *P < 0.05