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Table 1 Correlation of Aurora-B protein expression levels in OS tissues with clinical pathologic parameters

From: Aurora-B knockdown inhibits osteosarcoma metastasis by inducing autophagy via the mTOR/ULK1 pathway

Variables All cases Aurora-B expression P value
Low High
Gender
 Male 40 19 (47.5%) 21 (52.5%) 0.328
 Female 29 18 (62.1%) 11 (37.9%)  
Age
  ≤ 20 33 19 (57.6%) 14 (42.4%) 0.631
  > 20 36 18 (50%) 18 (50%)  
Location
 Femur/Tibia 53 27 (50.9%) 26 (49.1%) 0.569
 Elsewhere 16 10 (62.5%) 6 (37.5%)  
Tumor size (cm)
  ≤ 5 23 16 (69.6%) 7 (30.4%) 0.076
  > 5 46 21 (45.7%) 25 (54.3%)  
Enneking staging
 I + IIA 40 26 (65%) 14 (35%) 0.031*
 IIB + III 29 11 (37.9%) 18 (62.1%)  
LC3B expression
 Low 34 13 (38.2%) 21 (61.8%) 0.016*
 High 35 24 (68.6%) 11 (31.4%)  
  1. P value was calculated by Pearson’s Chi-Square test. *P < 0.05
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