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Fig. 7 | Cancer Cell International

Fig. 7

From: miR-335-5p suppresses gastric cancer progression by targeting MAPK10

Fig. 7

miR-335-5p inhibited cell invasion via MAPK10 knockdown. a Wound-healing assays of MKN-28 and SGC-7901 cells after treatment with si-ctrl and si-MAPK10. Representative images were captured at 0 h, 24 h, 48 h, and 72 h after transfection with si-ctrl and si-MAPK10. b The invasion viability of MKN-28 and SGC-7901 cells transfected with siMAPK10 was determined by a Transwell invasion assay. c The expression levels of MAPK10 were measured by western blotting in MKN-28/SGC-7901 cells transfected with siMAPK10. Protein expression levels of CDK6, CDK4, CyclinD1, BCL-2, BAX, E-cadherin, Vimentin, and β-catenin in gastric cancer cells transfected with siMAPK10 or si-ctrl were analyzed by western blotting. d Proposed model for the suppressive effect of miR-335-5p on gastric cancer progression via MAPK10 knockdown

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