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Fig. 7 | Cancer Cell International

Fig. 7

From: Inhibition of cancer cell-derived exosomal microRNA-183 suppresses cell growth and metastasis in prostate cancer by upregulating TPM1

Fig. 7

Inhibition of the expression of exosomal miR-183 impedes the development of prostate tumors. a Volume changes of tumor growth (n = 6). b Weight change of tumor growth (n = 6). c The expression of miR-183 and TPM1 in tumor tissues of nude mice detected by RT-qPCR assay. d Apoptosis in tumor tissues of nude mice detected by TUNEL assay (× 200). *p < 0.05 vs. exo-inhibitor-NC. exo-inhibitor-NC refers to mice injected with exosomes derived from inhibitor-NC transfected-LNCaP cells. exo-miR-183-inhibitor refers to mice injected with exosomes derived from miR-183-inhibitor transfected-LNCaP cells. Measurement data were expressed as mean ± standard deviation. Statistical analysis in relation to time-based measurements within each group was realized using repeated measurement ANOVA, followed by a Bonferroni’s post-hoc test. Each experiment was repeated three times

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Cancer Cell International

ISSN: 1475-2867

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