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Fig. 6 | Cancer Cell International

Fig. 6

From: YAP manipulates proliferation via PTEN/AKT/mTOR-mediated autophagy in lung adenocarcinomas

Fig. 6

Knockdown of YAP inhibited tumor growth through autophagy in vivo. a Image of tumor size in A549 cells tumor xenograft treated with control, siYAP and siYAP + 3MA. b, c Represented figure indicated the tumor growth after intraperitoneal injection with or without 3MA. d  Immune staining indicated the expression of p62 and LC3 II, scale bar = 200 µm. ef Western blot showed the expressive levels of YAP, p62, and LC3I/II in tumor tissues treated with or without siYAP and 3MA. Data were shown as the Mean ± SD (one-way analysis, *P < 0.05, **P < 0.01, ***P < 0.001)

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