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Fig. 2 | Cancer Cell International

Fig. 2

From: CircRNA PIP5K1A promotes the progression of glioma through upregulation of the TCF12/PI3K/AKT pathway by sponging miR-515-5p

Fig. 2

The influence of CircPIP5K1A on glioma cell proliferation, invasion, apoptosis and EMT. a CircPIP5K1A overexpression and knockdown models were constructed in glioma cell lines U87 and A172, respectively. B-D: CCK-8 method (b, c) and BrdU assay (d) were adopted to determine cell proliferation. e, f flow cytometry and western blot were conducted to detect the apoptosis of U87 and A172 cells. g Transwell assay was employed to determine the invasive ability of U87 and A172 cells. H: Western blot was employed to test EMT markers of E-cadherin, Vimentin and N-cadherin. *P < 0.05, **P < 0.01, ***P < 0.001

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