Fig. 4

CircPTPN22 promotes proliferation and metastasis of GC cell lines. a The expression levels of circPTPN22 in GC cell lines. b The efficiency of plasmid transfection in MKN-1 and AGS cells. c–e CCK8 assay and colony formation assay, cell proliferation was affected after circPTPN22 was knocked down. f–i Transwell assay verified the transferability after circPTPN22 was knocked down. j, k Cellular wound-healing assay was used to detect the motor ability of cells