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Fig. 1 | Cancer Cell International

Fig. 1

From: Circ_ZFR contributes to the paclitaxel resistance and progression of non-small cell lung cancer by upregulating KPNA4 through sponging miR-195-5p

Fig. 1

High level of circ_ZFR was observed in PTX-resistant NSCLC tissues and cells. a The expression level of circ_ZFR in normal tissues, PTX-sensitive and PTX-resistant NSCLC tissues was determined by qRT-PCR assay. b The expression of circ_ZFR in HBE, A549, H460, A549/PTX and H460/PTX cells was examined by qRT-PCR assay. c IC50 of PTX in A549/PTX and H460/PTX cells was measured by MTT assay. d, e After total RNA from A549 and H460 cells was treated with or without RNase R, qRT-PCR assay was performed for the levels of circ_ZFR and ZFR. f, g The expression levels of circ_ZFR and ZFR in the nuclear and cytosolic fractions of A549 and H460 cells were measured by qRT-PCR assay. *P < 0.05

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Cancer Cell International

ISSN: 1475-2867

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