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Table 1 The proportion of circRNAs with different functions in cancers

From: Cancer-related circular RNA: diverse biological functions

The types of cancers Acting as miRNA sponge Regulating transcription Binding to protein Translating to protein Other function
Hepatocellular carcinoma 79.6% (39/49) 2.0% (1/49) 4.1% (2/49) 2.0% (1/49) 12.2% (6/49)
Lung cancer 79.4% (27/34) 2.9% (1/34) / / 17.6% (6/34)
Breast cancer 87.9% (29/33) / 3.0% (1/33) / 9.1% (3/33)
Gastric cancer 84.8% (28/33) 3.0% (1/33) 6.1% (2/33) / 9.1% (3/33)
Glioma 82.6% (19/23) / 4.3% (1/23) 8.7% (2/23) 4.3% (1/23)
Colorectal cancer 69.6% (16/23) 4.3% (1/23) 8.7% (2/23) / 17.4% (4/23)
Bladder cancer 94.7% (18/19) / / / 5.3% (1/19)
Osteosarcoma 88.2% (15/17) 5.9% (1/17) 5.9% (1/17) / 5.9% (1/17)
Cervical cancer 88.9% (8/9) / / / 11.1% (1/9)
Oral squamous cell carcinomas 55.6% (5/9) / / / 44.4% (4/9)
Leukemia 85.7% (6/7) / 14.3% (1/7) / /
Esophageal squamous cell carcinoma 71.4% (5/7) / / / 28.6% (2/7)
Pancreatic cancer 100.0% (6/6) / / / /
Pancreatic ductal adenocarcinoma 100.0% (6/6) / / / /
Glioblastoma 66.7% (4/6) / / 16.7% (1/6) 16.7% (1/6)
Prostate cancer 75.0% (3/4) / / / 25.0% (1/4)
Nasopharyngeal carcinoma 100.0% (3/3) / / / /
Renal carcinoma 100.0% (3/3) / / / /
Papillary thyroid carcinoma 100.0% (2/2) / / / /
Cutaneous squamous cell carcinoma 100.0% (1/1) / / / /