Fig. 2

LINC00342 requires for the proliferation, migration and invasion of CRC cells. SW480 and HT-29 cells were infected with lentivirus containing sh-NC or sh-LINC00342. The transfection efficiency was confirmed by real-time PCR (a) and green fluorescence microscopy (b); cell proliferation was measured with CCK-8 (c) and colony formation (d) assays; cell migration and invasion was determined by wound healing assay (e) and transwell migration and invasion assays (f); the protein levels of E-cadherin and Vimentin were measured by western blotting (g). *P < 0.05, **P < 0.01 vs. sh-NC group