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Fig. 4 | Cancer Cell International

Fig. 4

From: LINC00963 affects the development of colorectal cancer via MiR-532-3p/HMGA2 axis

Fig. 4

Silencing LINC00963 inhibited colon cancer cell invasion and migration-related protein expression, and overexpression of LINC00963 had the opposite effect. ad The effect of overexpression or silencing of LINC00963 on colon cancer cell invasion was examined by Transwell. eh LINC00963 overexpression promoted the expressions of MMP-3 and MMP-9, and silencing LINC00963 inhibited the expression of MMP-3 and MMP-9. The experiment was repeated three times independently. GAPDH served as a control. ***P < 0.001 vs siNC; ^^^P < 0.001vs NC

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