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Fig. 6 | Cancer Cell International

Fig. 6

From: LINC00963 affects the development of colorectal cancer via MiR-532-3p/HMGA2 axis

Fig. 6

LINC00963 can target miR-532-3p to regulate HMGA2 expression. a The Venny map of miR-532-3p possible target gene, predicted by StarBase, Targetscan7.2, miRDB, miRBase database. b RT-qPCR was used to detect the expression of miR-532-3p in the Blank, siNC + IC, siLINC00963 + IC, siLINC00963 + I, siNC + I groups. c The expression of miR-532-3p in the Blank, NC + MC, LINC00963 + MC, LINC00963 + M, and NC + M groups was detected by RT-qPCR. d, e The effects of LINC00963 and miR-532-3p on the expressions of DDOST, HMGA2, MBD1, PISD, TARS were detected by RT-qPCR. U6 and GAPDH served as controls. The experiment was independently repeated three times. RT-qPCR: real-time quantitative polymerase chain reaction. *P < 0.05, ***P < 0.001 vs siNC + IC; ##P < 0.01, ###P < 0.001 vs siNC + I; ^^^P < 0.001 vs siLINC + IC; &P < 0.05, &&&P < 0.001 vs NC + MC; P < 0.001 vs LINC + MC; +++P < 0.001 vs NC + M

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