Fig. 9
From: LINC00963 affects the development of colorectal cancer via MiR-532-3p/HMGA2 axis
Effect of miR-532-3p targeting HMGA2 on invasion and migration-related proteins of CRC cells. a–d MiR-532-3p inhibitor and HMGA2 overexpression promoted cell invasion; miR-532-3p mimic and silent HMGA2 inhibited cell invasion. e–h The effects of miR-532-3p and HMGA2 on the expressions of MMP-3 and MMP-9 were determined by Western blot. GAPDH served as a control. The experiment was repeated three times independently. ***P < 0.001 vs IC + siNC; ###P < 0.001 vs I + siNC; ^^^P < 0.001 vs IC + siHMGA2; &&&P < 0.001 vs MC + NC; △△△P < 0.001 vs MC + HMGA2; +++P < 0.001 vs M + NC