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Fig. 3 | Cancer Cell International

Fig. 3

From: PPP2R2B downregulation is associated with immune evasion and predicts poor clinical outcomes in triple-negative breast cancer

Fig. 3

PPP2R2B was identified as a hub prognostic biomarker and associated with malignant progression of breast cancer. a Through Lasso penalized Cox regression analysis with 1000 iterations, a signature containing 4 genes was identified as an optimal signature with maximum 5 year AUC value. b The expression difference of 4 signature genes between breast normal tissues and TNBC tissues in TCGA. c Immunohistochemistry staining of PPP2R2B expression in breast normal tissues and TNBC tissues. d Quantitative real-time PCR analysis. e Kaplan‐Meier survival analysis of PPP2R2B in multiple TNBC datasets. ns Not significant, *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001

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Cancer Cell International

ISSN: 1475-2867

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