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Fig. 7 | Cancer Cell International

Fig. 7

From: PPP2R2B downregulation is associated with immune evasion and predicts poor clinical outcomes in triple-negative breast cancer

Fig. 7

Further evaluation of PPP2R2B related immunity functions in TNBC. a, b The relationship between PPP2R2B expression and T cell immunity in TCGA and METABRIC, respectively. ce The most related immune checkpoint family genes with PPP2R2B expression in TCGA. fh The most related immune checkpoint family genes with PPP2R2B expression in METABRIC. GO:0002842 positive regulation of T cell mediated immune response to tumor cell; GO:0019882 antigen processing and presentation; GO:0042110 T cell activation; GO:0046631 alpha–beta T cell activation; GO:0046632 alpha–beta T cell differentiation; GO:2000553 positive regulation of T-helper 2 cell cytokine production; GO:2000556 positive regulation of T-helper 1 cell cytokine production. ns (Not significant), *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001

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