Table 1 Clinicopathological characteristics of patients with invasive BrCa (N = 206)
Variable | Total patients (n) | The relative frequency (%) | P-value* |
|---|---|---|---|
Age at diagnosis (year) | |||
Mean ± S.D. | 46.65 ± 8.61 | ||
< 48 | 117 | 56.8 | 0.051 |
≥ 48 | 89 | 43.2 | |
Age at first pregnancy (year) | |||
Mean ± S.D. | 22.11 ± 4.86 | ||
< 24 | 120 | 60.6 | 0.003 |
≥ 24 | 78 | 39.4 | |
Age at menopause (year) | |||
Mean ± S.D. | 47.86 ± 4.73 | ||
Post-menopause | 69 | 33.5 | <0.001 |
Pre-menopause | 137 | 66.5 | |
Age at menarche (year) | |||
Mean ± S.D. | 13.52 ± 1.36 | ||
< 13 | 40 | 19.9 | <0.001 |
≥ 13 | 161 | 80.1 | |
Tumor type | |||
IDC | 172 | 92.0 | <0.001 |
Others | 15 | 8.0 | |
Tumor size (cm) | |||
Mean ± S.D. | 2.96 ± 1.35 | ||
T1 (size ≤ 2) | 59 | 31.7 | <0.001 |
T2 (2 < size ≤ 5) | 114 | 61.3 | |
T3 (size > 5) | 13 | 7.0 | |
Histologic grade | |||
I | 39 | 20.9 | <0.001 |
II | 126 | 67.4 | |
III | 22 | 11.7 | |
Axillary lymph node metastasis | |||
Negative | 64 | 34.8 | <0.001 |
Positive | 120 | 65.2 | |
Tumor stage | |||
I | 55 | 30.4 | <0.001 |
II | 119 | 65.7 | |
III | 7 | 3.9 | |
ER | |||
Negative | 23 | 12.7 | <0.001 |
Positive | 158 | 87.3 | |
PR | |||
Negative | 27 | 14.9 | <0.001 |
Positive | 154 | 85.1 | |
HER2 | |||
Negative | 144 | 79.6 | <0.001 |
Positive | 37 | 20.4 | |
Molecular subtype | |||
Luminal A (ER ± , PR ± , and HER2-) | 135 | 74.6 | <0.001 |
Luminal B (ER ± , PR ± , and HER2 +) | 23 | 12.7 | |
HER2 rich (ER-, PR-, and HER2 +) | 14 | 7.7 | |
Triple-negative (ER-, PR-, and HER2-) | 9 | 5.0 | |