CTTN (n = 174) | RhoA (n = 205) | ROCK (n = 202) | CLDN-1 (n = 206) | CLDN-2 (n = 110) | CLDN-4 (n = 206) | |
---|---|---|---|---|---|---|
Total population | ||||||
CTTN | 1 | |||||
RhoA | 0.065 (0.395)* | 1 | ||||
ROCK | 0.170 (0.028) | 0.246 (< 0.001) | 1 | |||
CLDN-1 | − 0.036 (0.646) | − 0.007 (0.917) | − 0.062 (0.391) | 1 | ||
CLDN-2 | 0.043 (0.686) | − 0.017 (0.866) | 0.237 (0.014) | 0.034 (0.727) | 1 | |
CLDN-4 | 0.013 (0.868) | 0.086 (0.228) | − 0.023 (0.752) | 0.411 (< 0.001) | − 0.102 (0.292) | 1 |
ER- and PR ± (n = 23) | ||||||
CTTN | 1 | |||||
RhoA | 0.182 (0.465) | 1 | ||||
ROCK | 0.398 (0.091) | 0.397 (0.067) | 1 | |||
CLDN-1 | 0.198 (0.415) | 0.009 (0.967) | − 0.049 (0.832) | 1 | ||
CLDN-2 | 0.655 (0.029) | − 0.247 (0.465) | − 0.285 (0.396) | − 0.316 (0.344) | 1 | |
CLDN-4 | − 0.027 (0.914) | 0.077 (0.748) | 0.007 (0.975) | 0.095 (0.691) | − 0.366 (0.299) | 1 |
ER + and PR ± (n = 158) | ||||||
CTTN | 1 | |||||
RhoA | 0.074 (0.404) | 1 | ||||
ROCK | 0.128 (0.153) | 0.280 (0.001) | 1 | |||
CLDN-1 | -0.065 (0.469) | − 0.001 (0.994) | − 0.066 (0.433) | 1 | ||
CLDN-2 | 0.033 (0.786) | − 0.005 (0.965) | 0.267 (0.016) | 0.020 (0.858) | 1 | |
CLDN-4 | 0.016 (0.859) | 0.086 (0.301) | − 0.015 (0.862) | 0.451 (< 0.001) | − 0.119 (0.284) | 1 |
ALNM– (n = 64) | ||||||
CTTN | 1 | |||||
RhoA | − 0.056 (0.705) | 1 | ||||
ROCK | − 0.049 (0.741) | 0.233 (0.083) | 1 | |||
CLDN-1 | 0.070 (0.638) | 0.011 (0.932) | − 0.166 (0.217) | 1 | ||
CLDN-2 | − 0.041 (0.847) | 0.166 (0.382) | 0.733 (< 0.001) | − 0.045 (0.810) | 1 | |
CLDN-4 | 0.022 (0.882) | 0.103 (0.446) | − 0.194 (0.151) | 0.522 (< 0.001) | − 0.131 (0.490) | 1 |
ALNM + (n = 120) | ||||||
CTTN | 1 | |||||
RhoA | 0.129 (0.204) | 1 | ||||
ROCK | 0.226 (0.027) | 0.311 (0.001) | 1 | |||
CLDN-1 | − 0.079 (0.448) | − 0.010 (0.921) | 0.040 (0.681) | 1 | ||
CLDN-2 | 0.121 (0.384) | − 0.160 (0.219) | − 0.098 (0.443) | 0.004 (0.976) | 1 | |
CLDN-4 | 0.030 (0.769) | 0.068 (0.479) | 0.029 (0.763) | 0.377 (< 0.001) | − 0.028 (0.826) | 1 |
Stage I (n = 55) | ||||||
CTTN | 1 | |||||
RhoA | 0.060 (0.710) | 1 | ||||
ROCK | 0.519 (0.001) | 0.252 (0.077) | 1 | |||
CLDN-1 | − 0.025 (0.877) | − 0.060 (0.674) | − 0.115 (0.422) | 1 | ||
CLDN-2 | − 0.064 (0.766) | 0.204 (0.298) | 0.741 (< 0.001) | − 0.049 (0.800) | 1 | |
CLDN-4 | 0.232 (0.144) | 0.039 (0.758) | 0.002 (0.990) | 0.389 (0.004) | − 0.136 (0.480) | 1 |
Stages II-III (n = 126) | ||||||
CTTN | 1 | |||||
RhoA | 0.098 (0.329) | 1 | ||||
ROCK | 0.069 (0.496) | 0.308 (0.001) | 1 | |||
CLDN-1 | 0.002 (0.980) | 0.022 (0.818) | 0.002 (0.987) | 1 | ||
CLDN-2 | 0.130 (0.359) | − 0.163 (0.213) | − 0.130 (0.324) | 0.013 (0.923) | 1 | |
CLDN-4 | − 0.052 (0.609) | 0.085 (0.375) | − 0.019 (0.842) | 0.429 (< 0.001) | − 0.014 (0.917) | 1 |