Table 2 XPF expression in CRC and nontumor adjacent tissue
From: XPF expression and its relationship with the risk and prognosis of colorectal cancer
Category | Group | Cases | (−) | (+) | (++) | (+++) | PR (%) | P |
|---|---|---|---|---|---|---|---|---|
n (%) | n (%) | n (%) | n (%) | |||||
Overall | CRC | 230 | 115 | 94 | 15 | 6 | 50.0% | <0.001 |
Adjacent | 230 | 228 | 1 | 1 | 0 | 0.9% | ||
Male | CRC | 129 | 59 | 57 | 9 | 4 | 54.3% | <0.001 |
Adjacent | 129 | 127 | 1 | 1 | 0 | 1.6% | ||
Female | CRC | 101 | 56 | 37 | 6 | 2 | 44.6% | <0.001 |
Adjacent | 101 | 101 | 0 | 0 | 0 | 0.0% | ||
≤60 | CRC | 112 | 58 | 45 | 7 | 2 | 48.2% | <0.001 |
Adjacent | 112 | 111 | 1 | 0 | 0 | 0.9% | ||
>60 | CRC | 118 | 57 | 49 | 8 | 4 | 51.7% | <0.001 |
Adjacent | 118 | 117 | 0 | 1 | 0 | 0.8% | ||
Smoking | CRC | 54 | 26 | 22 | 2 | 4 | 51.9% | <0.001 |
Adjacent | 54 | 53 | 1 | 0 | 0 | 1.9% | ||
No smoking | CRC | 176 | 89 | 72 | 13 | 2 | 49.4% | <0.001 |
Adjacent | 176 | 175 | 0 | 1 | 0 | 0.6% | ||
Drinking | CRC | 36 | 19 | 15 | 1 | 1 | 47.2% | <0.001 |
Adjacent | 36 | 36 | 0 | 0 | 0 | 0.0% | ||
No drinking | CRC | 194 | 96 | 79 | 14 | 5 | 50.5% | <0.001 |
Adjacent | 194 | 192 | 1 | 1 | 0 | 1.0% | ||
Colon | CRC | 74 | 48 | 21 | 3 | 2 | 35.1% | <0.001 |
Adjacent | 74 | 74 | 0 | 0 | 0 | 0.0% | ||
Rectum | CRC | 156 | 67 | 73 | 12 | 4 | 57.1% | <0.001 |
Adjacent | 156 | 154 | 1 | 1 | 0 | 1.3% | ||
Lymph node metastasis | CRC | 134 | 72 | 51 | 8 | 3 | 46.3% | <0.001 |
Adjacent | 134 | 133 | 1 | 0 | 0 | 0.7% | ||
Without Lymph node metastasis | CRC | 96 | 43 | 43 | 7 | 3 | 55.2% | <0.001 |
Adjacent | 96 | 95 | 0 | 1 | 0 | 1.0% | ||
Distant metastasis | CRC | 57 | 26 | 25 | 3 | 3 | 54.4% | <0.001 |
Adjacent | 57 | 56 | 1 | 0 | 0 | 1.8% | ||
No Distant metastasis | CRC | 173 | 89 | 69 | 12 | 3 | 48.6% | <0.001 |
Adjacent | 173 | 172 | 0 | 1 | 0 | 0.6% | ||
Perineural invasion | CRC | 136 | 72 | 52 | 9 | 3 | 47.1% | <0.001 |
Adjacent | 136 | 135 | 0 | 1 | 0 | 0.7% | ||
Without Perineural invasion | CRC | 94 | 43 | 42 | 6 | 3 | 54.3% | <0.001 |
Adjacent | 94 | 93 | 1 | 0 | 0 | 1.1% | ||
Vessel carcinoma embolus | CRC | 53 | 31 | 19 | 3 | 0 | 41.5% | <0.001 |
Adjacent | 53 | 53 | 0 | 0 | 0 | 0.0% | ||
Without Vessel carcinoma embolus | CRC | 177 | 84 | 75 | 12 | 6 | 52.5% | <0.001 |
Adjacent | 177 | 175 | 1 | 1 | 0 | 1.1% | ||
Infiltrative | CRC | 139 | 76 | 54 | 5 | 4 | 45.3% | <0.001 |
Adjacent | 139 | 138 | 0 | 1 | 0 | 0.7% | ||
Nested/cloddy | CRC | 91 | 39 | 40 | 10 | 2 | 57.1% | <0.001 |
Adjacent | 91 | 90 | 1 | 0 | 0 | 1.1% | ||
Poor/mucinous | CRC | 70 | 41 | 24 | 4 | 1 | 41.4% | <0.001 |
Adjacent | 70 | 69 | 1 | 0 | 0 | 1.4% | ||
Well/moderate | CRC | 160 | 74 | 70 | 11 | 5 | 53.8% | <0.001 |
Adjacent | 160 | 159 | 0 | 1 | 0 | 0.6% | ||
Family history | CRC | 41 | 21 | 14 | 4 | 2 | 48.8% | <0.001 |
Adjacent | 41 | 40 | 1 | 0 | 0 | 2.4% | ||
Without Family history | CRC | 189 | 94 | 80 | 11 | 4 | 50.3% | <0.001 |
Adjacent | 189 | 188 | 0 | 1 | 0 | 0.5% | ||
T1 | CRC | 6 | 2 | 3 | 1 | 0 | 66.7% | |
Adjacent | 6 | 6 | 0 | 0 | 0 | 0.0% | 0.022 | |
T2 | CRC | 85 | 34 | 42 | 7 | 2 | 60.0% | |
Adjacent | 85 | 84 | 0 | 1 | 0 | 1.2% | <0.001 | |
T3 | CRC | 119 | 68 | 43 | 5 | 3 | 42.9% | |
Adjacent | 119 | 118 | 1 | 0 | 0 | 0.8% | <0.001 | |
T4 | CRC | 18 | 10 | 5 | 2 | 1 | 44.4% | |
Adjacent | 18 | 18 | 0 | 0 | 0 | 0.0% | 0.002 | |
T1-2 | CRC | 42 | 19 | 18 | 3 | 2 | 54.8% | |
Adjacent | 42 | 41 | 0 | 1 | 0 | 2.4% | <0.001 | |
T3-4 | CRC | 141 | 78 | 51 | 8 | 4 | 44.7% | |
Adjacent | 141 | 140 | 1 | 0 | 0 | 0.7% | <0.001 |