Fig. 2

Effect of emodin on the HA-CD44/RHAMM signaling pathway in lung cancer cell lines. Cells were exposed to 30 µM emodin for 24 h before the western blotting assay. a The suppression rate of emodin on cell viability was plotted vs. suppression rate of emodin on HA secretion. d Representative image of western blotting. c–f The effect of emodin on the protein expression of HAS2, HAS3, CD44, and RHAMM in lung cancer cell lines (Bar chart for western blotting). “*” marks the significant difference (p < 0.05) compare with the control (0 µM or “−”)