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Fig. 3 | Cancer Cell International

Fig. 3

From: PlGF knockdown attenuates hypoxia-induced stimulation of cell proliferation and glycolysis of lung adenocarcinoma through inhibiting Wnt/β-catenin pathway

Fig. 3

Hypoxia induced up-regulation of HIF-1α and PlGF in H1975 and H358 cells. a, b Cells are cultured under hypoxia (90% N2, 5% CO2 and 5% O2) or normoxia (5% CO2 and 95% air, control) for 12 h, 24 h, and 48 h. mRNA and protein levels of HIF-1α and PlGF in H1975 (a) and H358 (b) are compared between the hypoxic and normoxic conditions. *p < 0.05, **p < 0.01, ***p < 0.001 vs. Control

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