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Fig. 1 | Cancer Cell International

Fig. 1

From: MicroRNA regulation of cancer stem cells in the pathogenesis of breast cancer

Fig. 1

miRNAs act as suppressors or oncomiRs in BCSC maintenance. miRNAs can both act as suppressors (red background) or oncomiRs (green background) to influence BCSC activities independently of known signaling pathways (left panel). On the other hand, some miRNAs can be placed into well-defined signaling pathways (right panel, different color backgrounds) by positively or negatively regulating the characteristics and development of BCSCs such as self-renewal or chemoresistance capacities

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