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Fig. 3 | Cancer Cell International

Fig. 3

From: Anlotinib as a promising inhibitor on tumor growth of oral squamous cell carcinoma through cell apoptosis and mitotic catastrophe

Fig. 3

Cell cycle arrest and cell apoptosis were induced by Anlotinib. Cells were treated with Anlotinib for 24 h before harvest for flow cytometry to detect cell cycle distribution, and for 48 h to detect cell apoptotic percentage. The results demonstrated cell cycle percentage of G2 was significantly raised from 8.94% (Cal-27) and 15.21% (SCC-25) to 12.66% and 30.25% (a–d). Cell apoptotic percentage (early apoptosis and total apoptosis) was significantly increased in groups treated with Anlotinib (e–h). (*p < 0.05, **p < 0.01)

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Cancer Cell International

ISSN: 1475-2867

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