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Table 2 Spearman analysis of correlation between TUG1 and clinicopathological

From: TRAIL promotes hepatocellular carcinoma apoptosis and inhibits proliferation and migration via interacting with IER3

Variables IER3 expression level
Spearman correlation p value
Age (years, < 50 vs. ≥ 50) − 0.129 0.224
Gender (male/female) 0.039 0.712
HBsAg (positive/negative) 0.179 0.094
HBcAb (positive/negative) 0.151 0.163
HCV (positive/negative) 0.099 0.359
Liver cirrhosis (yes/no) − 0.086 0.425
Total bilirubin (mmol/L, < 21 vs. ≥ 21) 0.09 0.403
ALT (U/L, < 60 vs. ≥ 60) − 0.179 0.094
GGT (U/L, < 40 vs. ≥ 40) − 0.23 0.03
Cirrhotic nodules (single/multiple) 0.032 0.768
Vascular invasion (yes/no) − 0.14 0.219
Tumor number (single/multiple) 0.001 0.994
Tumor size (cm, < 5 vs. ≥ 5) − 0.414  < 0.001
Recrudescence (yes/no) − 0.21 0.047
AJCC TNM stage (I + II vs III + IV) − 0.079 0.461
  1. Italics numbers indicate significant differences (P < 0.05)
  2. HCC hepatocellular carcinoma, HBsAg hepatitis B surface antigen, HBcAb hepatitis B core antigen, HCV hepatitis C virus, ALT alanine transaminase, GGT Gamma-Glutamyltransferase, AFP α-fetoprotein, AJCC the American Joint Committee on Cancer, TNM tumor-node-metastasis