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Table 3 Univariate and multivariate analyses of various prognostic parameters in patients with HCC Cox-regression analysis

From: TRAIL promotes hepatocellular carcinoma apoptosis and inhibits proliferation and migration via interacting with IER3

  Univariate analysis Multivariate analysis
p value Hazard Ratio 95% confidence interval p value Hazard Ratio 95% confidence interval
IER3 0.041 0.549 0.305–0.989 0.046252 0.596 0.246–1.444
Gender (male/female) 0.241 0.496 0.153–1.601 0.048 0.168 0.029–0.983
HBsAg (positive/negative) 0.906 1.045 0.502–2.175 0.037 0.276 0.082–0.924
GGT (U/L, < 40 vs. ≥ 40) 0.034 2.148 1.059–4.356 0.017 4.274 1.300–14.054
Cirrhotic nodules (single/multiple) 0.121 3.077 0.745–12.713 0.033 12.069 1.216–119.809
AJCC TNM stage (I + II vs III + IV) 0.021 4.115 1.237–13.688 0.857 0.792 0.062–10.152
  1. Italics numbers indicate significant differences (P < 0.05)
  2. HCC hepatocellular carcinoma, HBsAg hepatitis B surface antigen, GGT Gamma-Glutamyltransferase, AJCC the American Joint Committee on Cancer, TNM tumor-node-metastasis