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Fig. 1 | Cancer Cell International

Fig. 1

From: miR-636 inhibits EMT, cell proliferation and cell cycle of ovarian cancer by directly targeting transcription factor Gli2 involved in Hedgehog pathway

Fig. 1

Differential expression of miR-636, Hh and EMT markers in OVC. a Association analysis for Hh signaling pathway-related genes (each circle represents a gene and the edges between circles indicate associations); b Hh signaling pathway in KEGG database (red represents the location of Gli2 gene in the signaling pathway); c The intersection between genes predicted by TargetScan database and down-regulated DEmiRNAs; d Heat map shows the DEmiRNAs in GSE58517 dataset; e The expression of miR-636 in clinical cancer tissue samples (n = 30) and adjacent normal tissue samples (n = 30); f Differential expression of miR-636, Hh and EMT markers in OVC cells and normal ovarian cells detected by qRT-PCR; g The protein expression of Hh and EMT markers examined by Western blot; *p < 0.05, **p < 0.01

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Cancer Cell International

ISSN: 1475-2867

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