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Fig. 5 | Cancer Cell International

Fig. 5

From: Downregulation of tumor‐derived exosomal miR-34c induces cancer‐associated fibroblast activation to promote cholangiocarcinoma progress

Fig. 5

WNT1 suppression reverses the effect of miR-34c inhibition. a qRT-PCR analysis of expression of IL-1β, IL-6, and IL-8 in CCC-HSF-1 cells transfected with miR-34c inhibitor and/or WNT1 siRNA. b Migration assay analysis of CCC-HSF-1 cells transfected with miR-34c inhibitor and/or WNT1 siRNA or control. c Western blot analysis of fibrinogen and Wnt pathway-related proteins; Scale bar, 50 µm. *P < 0.05, **P < 0.01 vs. inhibitor NC + si-Ctrl groups;#P < 0.05, ##P < 0.01 vs. inhibitor NC + si-WNT1 groups

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Cancer Cell International

ISSN: 1475-2867

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