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Fig. 8 | Cancer Cell International

Fig. 8

From: Downregulation of tumor‐derived exosomal miR-34c induces cancer‐associated fibroblast activation to promote cholangiocarcinoma progress

Fig. 8

Activated fibroblasts promote cholangiocarcinoma progression via miR-34c. Xenograft tumorigenicity assay for nude mice injected with QBC939 cells pretreated with exosomes from CCC-HSF-1 cells incubated with or without miR-34c mimics. Representative tumors (upper panel) and measurement of tumor volume and weight (lower panel) are shown. **P < 0.01 vs. NCC-Exo; ##P < 0.01 vs. NC-Exo groups

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