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Table 1 ADAM10 expression level before and after neoadjuvant chemotherapy (NACT) in Cohort 1 and Cohort 2 according to different chemotherapy response

From: ADAM10 is involved in the oncogenic process and chemo-resistance of triple-negative breast cancer via regulating Notch1 signaling pathway, CD44 and PrPc

 

Pre-NACT (mean ± SE)

Post-NACT (mean ± SE)

p-value

Cohort 1 (n = 25)

172.4 ± 77.18

118.4 ± 86.98

0.039*

Cohort 2 (n = 69)

129.1 ± 88.04

170.6 ± 94.49

0.030*

p-value

0.023*

0.020*

 
  1. Cohort 1: Samples showing poor response to NACT
  2. Cohort 2: Samples showing good response to NACT
  3. *p < 0.05, **p < 0.01
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Cancer Cell International

ISSN: 1475-2867

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