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Table 1 Combination index (CI) for cell viability in GBM cell line U-87 MG treated with AZD6482 and URMC-099 (n = 3)

From: Synergism between the phosphatidylinositol 3-kinase p110β isoform inhibitor AZD6482 and the mixed lineage kinase 3 inhibitor URMC-099 on the blockade of glioblastoma cell motility and focal adhesion formation

AZD6482 (μM) URMC-099 (μM) CI*
6 1 0.8339 ± 0.2241
12 2 0.9744 ± 0.1801
18 3 0.9500 ± 0.2649
24 4 0.7481 ± 0.2051
30 5 0.5499 ± 0.1539
  1. * Data were presented as mean ± S.E.M. CI < 0.9 indicates synergistic effects; CI > 1.1 indicates antagonistic effects; CI between 0.9 and 1.1 indicates additive effects