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Table 1 Combination index (CI) for cell viability in GBM cell line U-87 MG treated with AZD6482 and URMC-099 (n = 3)

From: Synergism between the phosphatidylinositol 3-kinase p110β isoform inhibitor AZD6482 and the mixed lineage kinase 3 inhibitor URMC-099 on the blockade of glioblastoma cell motility and focal adhesion formation

AZD6482 (μM)

URMC-099 (μM)

CI*

6

1

0.8339 ± 0.2241

12

2

0.9744 ± 0.1801

18

3

0.9500 ± 0.2649

24

4

0.7481 ± 0.2051

30

5

0.5499 ± 0.1539

  1. * Data were presented as mean ± S.E.M. CI < 0.9 indicates synergistic effects; CI > 1.1 indicates antagonistic effects; CI between 0.9 and 1.1 indicates additive effects
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Cancer Cell International

ISSN: 1475-2867

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