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Table 2 Combination index (CI) for cell viability in GBM cell line U-118 MG treated with AZD6482 and URMC-099 (n = 3)

From: Synergism between the phosphatidylinositol 3-kinase p110β isoform inhibitor AZD6482 and the mixed lineage kinase 3 inhibitor URMC-099 on the blockade of glioblastoma cell motility and focal adhesion formation

AZD6482 (μM) URMC-099 (μM) CI*
10 1 102.4335 ± 54.5396
20 2 1.1831 ± 0.2560
30 3 0.4915 ± 0.0643
40 4 0.4713 ± 0.0718
50 5 0.4889 ± 0.1219
  1. * Data were presented as mean ± S.E.M. CI < 0.9 indicates synergistic effects; CI > 1.1 indicates antagonistic effects; CI between 0.9 and 1.1 indicates additive effects