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Table 2 The univariate and multivariate analyses of factors associated with overall survival

From: Co-expression of CMTM6 and PD-L1: a novel prognostic indicator of gastric cancer

Variable univariate Cox regression multivariate Cox regression
HR 95%CI P-value HR 95%CI P-value
Age (≥ 60) 1.224 0.839–1.785 0.295    
Sex (male) 1.016 0.677–1.526 0.937    
Size (≥ 5 cm) 1.678 1.085–2.595 0.02    
Differentiation (Poor) 0.773 0.504–1.185 0.773    
Tumor location (Middle low) 1.176 0.670–2.065 0.572    
Borrmann type (IV) 2.164 1.444–3.241 0.000 1.825 1.202–2.770 0.005
Invasive depth T3-T4 2.627 1.327–4.889 0.003    
lymph node metastasis ( +) 2.829 1.475–5.424 0.002 2.395 1.228–4.671 0.010
Peritoneal recurrence ( +) 1.919 1.263–2.914 0.002 1.704 1.102–2.637 0.017
High CMTM6 expression 1.668 1.032–2.695 0.037    
High PD-L1 expression 1.457 0.922–2.301 0.107    
CMTM6 + / PD-L1 +  1.757 1.162–2.655 0.007 1.554 1.011–2.389 0.044
  1. CMTM6 CKLF Like MARVEL Transmembrane Domain Containing 6, PD-L1 Programmed death ligand-1