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Fig. 6 | Cancer Cell International

Fig. 6

From: CircNEIL3 promotes cervical cancer cell proliferation by adsorbing miR-137 and upregulating KLF12

Fig. 6

CircNEIL3 adsorbed miR-137 and up-regulated KLF12 to regulate the proliferation of cervical cancer cells. a The expressions of KLF12 mRNA in SiHa and Hela transfected with si-NC + miR-NC, si-circNEIL3 + miR-NC, si-NC + miR-137 inhibitor, and si-circNEIL3 + miR-137 inhibitor were detected by qRT-PCR. b The expressions of KLF12 protein in SiHa and Hela transfected with si-NC + miR-NC, si-circNEIL3 + miR-NC, si-NC + miR-137 inhibitor, si-circNEIL3 + miR-137 inhibitor were detected by Western blotting. c, d CCK-8 proliferation assays of SiHa and Hela cells transfected with si-NC + miR-NC, si-circNEIL3 + miR-NC, si-NC + miR-137 inhibitor, and si-circNEIL3 + miR-137 inhibitor. e, f CCK-8 proliferation assays of SiHa and Hela cells transfected with control + si-NC, circNEIL3 + si-NC, control + si-KLF12, and circNEIL3 + si-KLF12. Data were represented as means ± S.D. of at least three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001

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