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Fig. 4 | Cancer Cell International

Fig. 4

From: Transcription elongation factor A-like 7, regulated by miR-758-3p inhibits the progression of melanoma through decreasing the expression levels of c-Myc and AKT1

Fig. 4

TCEAL7 inhibited the progression of melanoma through decreasing the expression of AKT1 and c-Myc. WM-115 and A375 cells were divided into Lenti-TCEAL7, Lenti-NC, Lenti-TCEAL7 + Lenti-AKT1/c-Myc and Lenti-AKT1/c-Myc groups and submitted to the following assays. ad Cell proliferation was detected by using the CCK-8 assay. e, f Transwell chamber assay was used to detect cell invasion. g, h Flow cytometry assay was applied to detect cell apoptosis. il Scratch assay was used to assess cell migration ability. (*P < 0.05 and ***P < 0.001, compared with Lenti-NC group; #P < 0.05 and ###P < 0.001, compared with Lenti-TCEAL7 group)

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