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Fig. 7 | Cancer Cell International

Fig. 7

From: Transcription elongation factor A-like 7, regulated by miR-758-3p inhibits the progression of melanoma through decreasing the expression levels of c-Myc and AKT1

Fig. 7

miR-758-3p promoted the tumorigenesis of melanoma cells via targeting TCEAL7. ab In vivo tumor formation assay was carried out to detect the tumorigenesis in A375 cells from mimic-NC + Lenti-NC, mimics + Lenti-NC and mimics + Lenti-TCEAL7 groups. c RT-PCR analysis of the expression levels of miR-758-3p in tumor tissues. d, e RT-PCR and western blotting assays were applied to detect the mRNA and protein levels of TCEAL7, AKT1, AKT2 and c-Myc in tumor tissues. (*P < 0.05 and **P < 0.01, compared with mimic-NC + Lenti-NC group; #P < 0.05, compared with mimics + Lenti-NC group)

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