|
Variable
|
Univariate analysis
|
Multivariate analysis
|
|---|
|
HR
|
95% CI
|
p
|
HR
|
95% CI
|
p
|
|---|
|
Overall survival
|
|
Age(year)
|
1.033
|
1.020–1.047
|
0.000
|
1.035
|
1.020–1.051
|
0.000
|
|
Gender
|
0.933
|
0.680–1.282
|
0.670
|
0.919
|
0.662–1.275
|
0.613
|
|
Race
|
1.193
|
0.716–1.988
|
0.498
|
1.169
|
0.670–2.039
|
0.582
|
|
Grade
|
1.967
|
1.6389-2.360
|
0.000
|
1.337
|
1.068–1.674
|
0.011
|
|
Stage
|
1.856
|
1.644–2.095
|
0.000
|
1.781
|
1.261–2.516
|
0.001
|
|
T
|
1.998
|
1.689–2.362
|
0.000
|
1.061
|
0.805–1.399
|
0.673
|
|
N
|
0.863
|
0.739–1.008
|
0.063
|
0.857
|
0.729–1.006
|
0.059
|
|
M
|
2.100
|
1.661–2.655
|
0.000
|
0.800
|
0.423–1.514
|
0.494
|
|
METTL14
|
0.663
|
0.574–0.766
|
0.000
|
0.808
|
0.691–0.946
|
0.008
|
- Italicized values indicated that p < 0.05
- HR hazard ratio, estimated from Cox proportional hazard regression model, CI confidence interval of the estimated HR; Multivariate models were adjusted for age, grade, race, stage and T,N,M classification
