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Fig. 3 | Cancer Cell International

Fig. 3

From: Hydrogen inhibits the proliferation and migration of gastric cancer cells by modulating lncRNA MALAT1/miR-124-3p/EZH2 axis

Fig. 3

H2 inhibited gastric cancer cell proliferation and migration through regulating lncRNA MALAT1. a Transcript levels of lncMALAT1 and EZH2 of MGC-803 cells were measured by quantitative real-time PCR. b Protein level of EZH2 was assessed by immunoblot. c MGC-803 and BGC-823 cells transfected with or without lncRNA MALAT1 expression vector were cultured with or without H2 for 24 h and assessed by MTT assay. d Scratch wound healing assay was used to examine the effects of H2 and lncRNA MALAT1 on MGC-803 and BGC-823 cell migration. Scale bar: 25 µm. Ctrl, Normal culture conditions. *p < 0.01 compared to Ctrl; #p < 0.01 compared to MALAT1; &p < 0.01 compared to H2

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