Skip to main content
Fig. 6 | Cancer Cell International

Fig. 6

From: ZEB1-AS1/miR-133a-3p/LPAR3/EGFR axis promotes the progression of thyroid cancer by regulating PI3K/AKT/mTOR pathway

Fig. 6

ZEB1-AS1 exerts oncogenic effect on TC progression by activating PI3K/AKT/mTOR pathway. a The levels of PI3K, AKT, mTOR and phosphorylated PI3K, AKT, mTOR were tested via western blot analysis in transfected cells. b, c Cell proliferation in cells transfected with sh-ZEB1-AS1#1 or sh-ZEB1-AS1#1 + IGF-1 was examined via CCK-8 and colony formation assays. Sh-NC was a negative control. d, e The apoptosis of transfected cells was evaluated via flow cytometry analysis and TUNEL assay. **P < 0.01

Back to article page