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Fig. 4 | Cancer Cell International

Fig. 4

From: SP1 induced long non-coding RNA LINC00958 overexpression facilitate cell proliferation, migration and invasion in lung adenocarcinoma via mediating miR-625-5p/CPSF7 axis

Fig. 4

CPSF7 is identified the molecular target of miR-625-5p and is regulated by LINC00958. a QRT-PCR was performed to detect the expression of target genes after transfecting with miR-625-5p mimics. b The expression profile of CPSF7 in LAD cell lines and normal pulmonic cell line was detected by qRT-PCR. c Putative miR-625-5p binding sites in 3′UTR sequence of CPSF7 on starBase. d Luciferase reporter assay was performed to determine the association between miR-625-5p and CPSF7. e RIP was used to verify the interaction of miR-625-5p and LINC00958, as well as miR-625-5p and CPSF7. f QRT-PCR was performed to study the effect of miR-625-5p on LINC00958 mediated CPSF7. **P < 0.01

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