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Table 2 Univariate and multivariate analyses of IRGS, clinical and pathologic factors of patients in training cohort

From: Immune-related gene signature for predicting the prognosis of head and neck squamous cell carcinoma

Characteristic

Univariate

Multivariate

HR (95% CI)

P value

HR (95% CI)

P value

IRGS

3.69 (2.73–4.98)

< 0.001

3.62 (2.58–5.09)

< 0.001

Age

1.02 (1.00–1.03)

0.01

1.02 (1.00–1.03)

< 0.01

Gender

0.71 (0.53-0.96)

0.03

0.90 (0.65–1.26)

0.55

TNM stage

1.38 (1.14–1.65)

< 0.001

1.24 (1.02–1.50)

0.03

Pathological grading

1.14 (0.93–1.39)

> 0.05

NA

NA

Smoking

NA

NA

NA

NA

Alcohol abuse

1.01 (0.74–1.37)

> 0.05

NA

NA

HPV

1.20 (0.88–1.63)

> 0.05

NA

NA