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Fig. 1 | Cancer Cell International

Fig. 1

From: Identification of a potentially functional circRNA–miRNA–mRNA regulatory network for investigating pathogenesis and providing possible biomarkers of bladder cancer

Fig. 1

Flowchart of the study. First, we downloaded microarray datasets from GEO to obtain DECs. Next, we intersected miRNAs that they sponge and differentially expressed miRNAs obtained from TCGA. Using similar methods, we obtained overlapping mRNAs and analyzed them for GO and KEGG analyses. Then, we selected nine candidate circRNAs and detected their expression by qRT-PCR. A regulatory network was successfully constructed around hsa_circ_0011385. Subsequently, we detected the expression of target miRNAs and identified hubgenes

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Cancer Cell International

ISSN: 1475-2867

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